Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
To address the mechanism by which the human globin genes are activated during erythropoiesis, we have used a tiled microarray to analyze the pattern of transcription factor binding and associated histone modifications across the telomeric region of human chromosome 16 in primary erythroid and nonery...
Váldodahkkit: | De Gobbi, M, Anguita, E, Hughes, J, Sloane-Stanley, J, Sharpe, J, Koch, C, Dunham, I, Gibbons, R, Wood, W, Higgs, D |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2007
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Geahča maid
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Differences in the patterns of transcription factor binding in the human and mouse alpha globin clusters point to potential differences in their regulation.
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Almmustuhtton: (2005) -
The mechanism of alpha-globin activation during erythropoiesis
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Is there a role for CTCF binding sites in regulating the structure or function of the a globin gene cluster?
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Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.
Dahkki: Anguita, E, et al.
Almmustuhtton: (2002) -
Deletion of the mouse alpha globin regulatory element (HS-26) has an unexpectedly mild phenotype.
Dahkki: Anguita, E, et al.
Almmustuhtton: (2003)