Hydrodynamic delivery of siRNA in a mouse model of sepsis

The use of siRNA in vivo as well as in animal models has become more widespread in recent years, leading to further questions as to the best mode of delivery that will achieve optimal knockdown. While the exact mechanism of siRNA uptake at a cellular level has yet to be fully elucidated, various del...

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Bibliographic Details
Main Authors: Wesche-Soldato, D, Lomas-Neira, J, Perl, M, Chung, C, Ayala, A
Format: Journal article
Language:English
Published: 2008