Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition.

Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition.

The highly diastereoselective anti-aminohydroxylation of (E)-gamma-tri-iso-propylsilyloxy-alpha,beta-unsaturated esters, via conjugate addition of lithium (S)-N-benzyl-N-(alpha-methylbenzyl)amide and subsequent in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziridine, has been used as the key...

Podrobná bibliografie
Hlavní autoři:	Abraham, E, Brock, E, Candela-Lena, J, Davies, S, Georgiou, M, Nicholson, R, Perkins, J, Roberts, P, Russell, A, Sánchez-Fernández, E, Scott, P, Smith, A, Thomson, J
Médium:	Journal article
Jazyk:	English
Vydáno:	2008

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