Bifunctional iminophosphorane-catalyzed enantioselective nitroalkane addition to unactivated α,β-unsaturated esters

Bifunctional iminophosphorane-catalyzed enantioselective nitroalkane addition to unactivated α,β-unsaturated esters

Herein we describe the enantioselective intermolecular conjugate addition of nitroalkanes to unactivated α,β-unsaturated esters, catalyzed by a bifunctional iminophosphorane (BIMP) superbase. The transformation provides the most direct access to pharmaceutically relevant enantioenriched γ-nitroester...

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Bibliografiska uppgifter
Huvudupphovsmän:	Rozsar, D, Farley, AJM, McLauchlan, I, Shennan, BDA, Yamazaki, K, Dixon, DJ
Materialtyp:	Journal article
Språk:	English
Publicerad:	Wiley 2023

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