A map of abstract relational knowledge in the human hippocampal–entorhinal cortex
The hippocampal–entorhinal system encodes a map of space that guides spatial navigation. Goal-directed behaviour outside of spatial navigation similarly requires a representation of abstract forms of relational knowledge. This information relies on the same neural system, but it is not known whether...
| Main Authors: | , , |
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| Format: | Journal article |
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eLife Sciences Publications
2017
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| _version_ | 1826303710228119552 |
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| author | Garvert, M Dolan, R Behrens, T |
| author_facet | Garvert, M Dolan, R Behrens, T |
| author_sort | Garvert, M |
| collection | OXFORD |
| description | The hippocampal–entorhinal system encodes a map of space that guides spatial navigation. Goal-directed behaviour outside of spatial navigation similarly requires a representation of abstract forms of relational knowledge. This information relies on the same neural system, but it is not known whether the organisational principles governing continuous maps may extend to the implicit encoding of discrete, non-spatial graphs. Here, we show that the human hippocampal–entorhinal system can represent relationships between objects using a metric that depends on associative strength. We reconstruct a map-like knowledge structure directly from a hippocampal–entorhinal functional magnetic resonance imaging adaptation signal in a situation where relationships are non-spatial rather than spatial, discrete rather than continuous, and unavailable to conscious awareness. Notably, the measure that best predicted a behavioural signature of implicit knowledge and blood oxygen level-dependent adaptation was a weighted sum of future states, akin to the successor representation that has been proposed to account for place and grid-cell firing patterns. |
| first_indexed | 2024-03-07T06:06:51Z |
| format | Journal article |
| id | oxford-uuid:ee24e77f-a2b5-4134-a3b3-4cf82cca60de |
| institution | University of Oxford |
| last_indexed | 2024-03-07T06:06:51Z |
| publishDate | 2017 |
| publisher | eLife Sciences Publications |
| record_format | dspace |
| spelling | oxford-uuid:ee24e77f-a2b5-4134-a3b3-4cf82cca60de2022-03-27T11:30:30ZA map of abstract relational knowledge in the human hippocampal–entorhinal cortexJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ee24e77f-a2b5-4134-a3b3-4cf82cca60deSymplectic Elements at OxfordeLife Sciences Publications2017Garvert, MDolan, RBehrens, TThe hippocampal–entorhinal system encodes a map of space that guides spatial navigation. Goal-directed behaviour outside of spatial navigation similarly requires a representation of abstract forms of relational knowledge. This information relies on the same neural system, but it is not known whether the organisational principles governing continuous maps may extend to the implicit encoding of discrete, non-spatial graphs. Here, we show that the human hippocampal–entorhinal system can represent relationships between objects using a metric that depends on associative strength. We reconstruct a map-like knowledge structure directly from a hippocampal–entorhinal functional magnetic resonance imaging adaptation signal in a situation where relationships are non-spatial rather than spatial, discrete rather than continuous, and unavailable to conscious awareness. Notably, the measure that best predicted a behavioural signature of implicit knowledge and blood oxygen level-dependent adaptation was a weighted sum of future states, akin to the successor representation that has been proposed to account for place and grid-cell firing patterns. |
| spellingShingle | Garvert, M Dolan, R Behrens, T A map of abstract relational knowledge in the human hippocampal–entorhinal cortex |
| title | A map of abstract relational knowledge in the human hippocampal–entorhinal cortex |
| title_full | A map of abstract relational knowledge in the human hippocampal–entorhinal cortex |
| title_fullStr | A map of abstract relational knowledge in the human hippocampal–entorhinal cortex |
| title_full_unstemmed | A map of abstract relational knowledge in the human hippocampal–entorhinal cortex |
| title_short | A map of abstract relational knowledge in the human hippocampal–entorhinal cortex |
| title_sort | map of abstract relational knowledge in the human hippocampal entorhinal cortex |
| work_keys_str_mv | AT garvertm amapofabstractrelationalknowledgeinthehumanhippocampalentorhinalcortex AT dolanr amapofabstractrelationalknowledgeinthehumanhippocampalentorhinalcortex AT behrenst amapofabstractrelationalknowledgeinthehumanhippocampalentorhinalcortex AT garvertm mapofabstractrelationalknowledgeinthehumanhippocampalentorhinalcortex AT dolanr mapofabstractrelationalknowledgeinthehumanhippocampalentorhinalcortex AT behrenst mapofabstractrelationalknowledgeinthehumanhippocampalentorhinalcortex |