Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis.

Revisiting the T-cell receptor alpha/delta locus and possible associations with multiple sclerosis.

A role for T cells in the pathogenesis of multiple sclerosis (MS) is well supported, evidenced by myriad immunological studies, as well as the unequivocal genetic influence of the major histocompatibility complex (MHC). Despite many attempts, no convincing genetic associations have been made between...

Bibliografski detalji
Glavni autori:	Watson, C, Para, A, Lincoln, MR, Ramagopalan, S, Orton, S, Morrison, K, Handunnetthi, L, Handel, A, Chao, M, Morahan, J, Sadovnick, A, Breden, F, Ebers, G
Format:	Journal article
Jezik:	English
Izdano:	2011

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Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians.
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Vitamin-D Receptor and 1-alpha-hydroxylase Genes in Risk and Outcome of Multiple Sclerosis in Canadians
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Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians
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Variants in ST8SIA1 do not play a major role in susceptibility to multiple sclerosis in Canadian families.
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No evidence for an effect of DNA methylation on multiple sclerosis severity at HLA-DRB1*15 or HLA-DRB5.
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Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis
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The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.
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Type 1 diabetes mellitus and multiple sclerosis: common etiological features.
od: Handel, A, i dr.
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Type 1 diabetes mellitus and multiple sclerosis: common etiological features
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Parental non-inherited HLA resistance alleles do not confer protection against multiple sclerosis.
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Genetic and Environmental Factors and the Distribution of Multiple Sclerosis in Europe
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Genetic and environmental factors and the distribution of multiple sclerosis in Europe.
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Epigenetic mechanisms in multiple sclerosis and the major histocompatibility complex (MHC).
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IGHV4-39 deletion polymorphism does not associate with risk or outcome of multiple sclerosis.
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Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.
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MHC transmission: insights into gender bias in MS susceptibility.
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Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis.
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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
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Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.
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Contribution of genetic, epigenetic and transcriptomic differences to twin discordance in multiple sclerosis.
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The inheritance of resistance alleles in multiple sclerosis.
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Of mice and men: experimental autoimmune encephalitis and multiple sclerosis.
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Parental transmission of HLA-DRB1*15 in multiple sclerosis.
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Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.
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Multiple sclerosis, vitamin D, and HLA-DRB1*15.
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Follow-up investigation of 12 proposed linkage regions in multiple sclerosis.
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The emerging role of vitamin D binding protein in multiple sclerosis.
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The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.
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Fine Mapping of Epigenetic Modifications in Multiple Sclerosis Susceptibility
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Analysis of 45 candidate genes for disease modifying activity in multiple sclerosis.
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Risk alleles for multiple sclerosis in multiplex families.
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Epistasis among HLA-DRB1, HLA-DQA1 and HLA-DQB1 Loci Determines Multiple Sclerosis Susceptibility
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Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene.
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Mother-child blood group incompatibility and the risk of multiple sclerosis.
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Sex ratio of multiple sclerosis in Canada: a longitudinal study.
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Parent-of-origin effects in MS: observations from avuncular pairs.
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Gestational diabetes and multiple sclerosis.
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Genomewide study of multiple sclerosis.
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Parent-of-origin effect in multiple sclerosis: observations from interracial matings.
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