Diagnosis of infection by frozen section during revision arthroplasty.
We assessed the efficacy of intraoperative frozen-section histology in detecting infection in failed arthroplasties in 106 hips and knees. We found inflammatory changes consistent with infection (an average of one or more neutrophil polymorphs or plasma cells per high-power field in several samples)...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1995
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| _version_ | 1826303721059909632 |
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| author | Athanasou, N Pandey, R de Steiger, R Crook, D Smith, P |
| author_facet | Athanasou, N Pandey, R de Steiger, R Crook, D Smith, P |
| author_sort | Athanasou, N |
| collection | OXFORD |
| description | We assessed the efficacy of intraoperative frozen-section histology in detecting infection in failed arthroplasties in 106 hips and knees. We found inflammatory changes consistent with infection (an average of one or more neutrophil polymorphs or plasma cells per high-power field in several samples) in 18 cases; there was a significant growth on bacterial culture in 20 cases. Compared with the bacterial cultures, the frozen sections provided two false-negative results and three false-positive results (sensitivity, 90%; specificity, 96%; and accuracy, 95%). The positive predictive value was 88%, the negative value, 98%. These results support the inclusion of intra-operative frozen-section histology in any protocol for revision arthroplasty for loose components. |
| first_indexed | 2024-03-07T06:07:01Z |
| format | Journal article |
| id | oxford-uuid:ee30c919-96b5-41ad-8159-492523644790 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:07:01Z |
| publishDate | 1995 |
| record_format | dspace |
| spelling | oxford-uuid:ee30c919-96b5-41ad-8159-4925236447902022-03-27T11:30:49ZDiagnosis of infection by frozen section during revision arthroplasty.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ee30c919-96b5-41ad-8159-492523644790EnglishSymplectic Elements at Oxford1995Athanasou, NPandey, Rde Steiger, RCrook, DSmith, PWe assessed the efficacy of intraoperative frozen-section histology in detecting infection in failed arthroplasties in 106 hips and knees. We found inflammatory changes consistent with infection (an average of one or more neutrophil polymorphs or plasma cells per high-power field in several samples) in 18 cases; there was a significant growth on bacterial culture in 20 cases. Compared with the bacterial cultures, the frozen sections provided two false-negative results and three false-positive results (sensitivity, 90%; specificity, 96%; and accuracy, 95%). The positive predictive value was 88%, the negative value, 98%. These results support the inclusion of intra-operative frozen-section histology in any protocol for revision arthroplasty for loose components. |
| spellingShingle | Athanasou, N Pandey, R de Steiger, R Crook, D Smith, P Diagnosis of infection by frozen section during revision arthroplasty. |
| title | Diagnosis of infection by frozen section during revision arthroplasty. |
| title_full | Diagnosis of infection by frozen section during revision arthroplasty. |
| title_fullStr | Diagnosis of infection by frozen section during revision arthroplasty. |
| title_full_unstemmed | Diagnosis of infection by frozen section during revision arthroplasty. |
| title_short | Diagnosis of infection by frozen section during revision arthroplasty. |
| title_sort | diagnosis of infection by frozen section during revision arthroplasty |
| work_keys_str_mv | AT athanasoun diagnosisofinfectionbyfrozensectionduringrevisionarthroplasty AT pandeyr diagnosisofinfectionbyfrozensectionduringrevisionarthroplasty AT desteigerr diagnosisofinfectionbyfrozensectionduringrevisionarthroplasty AT crookd diagnosisofinfectionbyfrozensectionduringrevisionarthroplasty AT smithp diagnosisofinfectionbyfrozensectionduringrevisionarthroplasty |