Single-cell transcriptomics of regulatory T Cells reveals trajectories of tissue adaptation

Single-cell transcriptomics of regulatory T Cells reveals trajectories of tissue adaptation

Non-lymphoid tissues (NLTs) harbor a pool of adaptive immune cells with largely unexplored phenotype and development. We used single-cell RNA-seq to characterize 35,000 CD4+ regulatory (Treg) and memory (Tmem) T cells in mouse skin and colon, their respective draining lymph nodes (LNs) and spleen. I...

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Библиографические подробности
Главные авторы: Miragaia, RJ, Gomes, T, Chomka, A, Jardine, L, Riedel, A, Hegazy, AN, Whibley, N, Tucci, A, Chen, X, Lindeman, I, Emerton, G, Krausgruber, T, Shields, J, Haniffa, M, Powrie, F, Teichmann, SA
Формат: Journal article
Язык:English
Опубликовано: Elsevier 2019

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