Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques.

Pulse field gradient NMR methods have been used to determine the effective hydrodynamic radii of a range of native and nonnative protein conformations. From these experimental data, empirical relationships between the measured hydrodynamic radius (R(h)) and the number of residues in the polypeptide...

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Autors principals: Wilkins, D, Grimshaw, S, Receveur, V, Dobson, C, Jones, J, Smith, L
Format: Journal article
Idioma:English
Publicat: 1999