Relationship of cell-free hemoglobin to impaired endothelial nitric oxide bioavailability and perfusion in severe falciparum malaria.

BACKGROUND: Hemolysis causes anemia in falciparum malaria, but its contribution to microvascular pathology in severe malaria (SM) is not well characterized. In other hemolytic diseases, release of cell-free hemoglobin causes nitric oxide (NO) quenching, endothelial activation, and vascular complica...

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Hlavní autoři: Yeo, T, Lampah, D, Tjitra, E, Gitawati, R, Kenangalem, E, Piera, K, Granger, D, Lopansri, B, Weinberg, J, Price, R, Duffull, S, Celermajer, D, Anstey, N
Médium: Journal article
Jazyk:English
Vydáno: 2009