HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition.
Cancer-associated epithelial to mesenchymal transition (EMT) is crucial for invasion and metastasis. Molecular hallmarks of EMT include down-regulation of the epithelial adhesion protein E-cadherin and de-novo expression of N-cadherin and the mesenchymal intermediate filament proteins vimentin and f...
Main Authors: | Hellner, K, Mar, J, Fang, F, Quackenbush, J, Münger, K |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2009
|
Similar Items
-
Tetraspanin in oncogenic epithelial-mesenchymal transition.
by: Muschel, R, et al.
Published: (2008) -
Characterization of Epithelial Progenitors in Normal Human Palatine Tonsils and Their HPV16 E6/E7-Induced Perturbation
by: Sung Yoon Catherine Kang, et al.
Published: (2015-12-01) -
Epithelial-mesenchymal transition
by: Kubik Joanna, et al.
Published: (2023-03-01) -
Physical Interaction between HPV16E7 and the Actin-Binding Protein Gelsolin Regulates Epithelial-Mesenchymal Transition via HIPPO-YAP Axis
by: Paola Matarrese, et al.
Published: (2021-01-01) -
HPV16 E6 mediates oncogenic transformation of cervical epithelial cells by downregulating DHRS2 expression
by: DU Xiurong, et al.
Published: (2024-04-01)