The association of autoimmune disorders with inflammatory bowel disease.

Medical records of patients with ulcerative colitis (n = 858), Crohn's disease (n = 378) and coeliac disease (n = 148) were examined to determine the prevalence of associated autoimmune disorders. Of outpatient controls (n = 300), 2 per cent had at least one autoimmune disorder, compared to 7 p...

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Main Authors: Snook, J, de Silva, H, Jewell, D
Format: Journal article
Language:English
Published: 1989
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author Snook, J
de Silva, H
Jewell, D
author_facet Snook, J
de Silva, H
Jewell, D
author_sort Snook, J
collection OXFORD
description Medical records of patients with ulcerative colitis (n = 858), Crohn's disease (n = 378) and coeliac disease (n = 148) were examined to determine the prevalence of associated autoimmune disorders. Of outpatient controls (n = 300), 2 per cent had at least one autoimmune disorder, compared to 7 per cent with ulcerative colitis, 2 per cent with Crohn's disease and 6 per cent with coeliac disease. Inclusion of primary sclerosing cholangitis with the autoimmune disorders increased the overall prevalence in ulcerative colitis to over 9 per cent. The results provide further indirect evidence of involvement of autoimmune mechanisms in the pathogenesis of ulcerative colitis.
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spelling oxford-uuid:eeaee6f5-a0a2-40c5-880a-ebb09b79c7272022-03-27T11:34:44ZThe association of autoimmune disorders with inflammatory bowel disease.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eeaee6f5-a0a2-40c5-880a-ebb09b79c727EnglishSymplectic Elements at Oxford1989Snook, Jde Silva, HJewell, DMedical records of patients with ulcerative colitis (n = 858), Crohn's disease (n = 378) and coeliac disease (n = 148) were examined to determine the prevalence of associated autoimmune disorders. Of outpatient controls (n = 300), 2 per cent had at least one autoimmune disorder, compared to 7 per cent with ulcerative colitis, 2 per cent with Crohn's disease and 6 per cent with coeliac disease. Inclusion of primary sclerosing cholangitis with the autoimmune disorders increased the overall prevalence in ulcerative colitis to over 9 per cent. The results provide further indirect evidence of involvement of autoimmune mechanisms in the pathogenesis of ulcerative colitis.
spellingShingle Snook, J
de Silva, H
Jewell, D
The association of autoimmune disorders with inflammatory bowel disease.
title The association of autoimmune disorders with inflammatory bowel disease.
title_full The association of autoimmune disorders with inflammatory bowel disease.
title_fullStr The association of autoimmune disorders with inflammatory bowel disease.
title_full_unstemmed The association of autoimmune disorders with inflammatory bowel disease.
title_short The association of autoimmune disorders with inflammatory bowel disease.
title_sort association of autoimmune disorders with inflammatory bowel disease
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