Control of immune pathology by regulatory T cells.

Control of immune pathology by regulatory T cells.

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CD4+CD25+ T(reg) cells inhibit colitis in the severe combined immune deficient (SCID) T cell adoptive transfer model. Cells with this function are present in the thymus suggesting that T(reg) cells capable of inhibiting bacteria-induced immune pathology are similar to those that inhibit organ-specif...

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Bibliografiske detaljer
Main Authors:	Powrie, F, Read, S, Mottet, C, Uhlig, H, Maloy, K
Format:	Journal article
Sprog:	English
Udgivet:	2003

Lignende værker

Control of intestinal inflammation by regulatory T cells
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Regulatory T cells in the control of immune pathology.
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Regulatory T Cells
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Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells.
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Homing of intestinal immune cells.
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Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells.
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Regulatory T cells and intestinal homeostasis.
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CD4+CD25+cells reverse established colitis in the CD4+CD45RBhigh adoptive transfer model of colitis.
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Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.
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CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms.
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Regulatory T cells and immune tolerance in the intestine.
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Induction of inflammatory bowel disease in immunodeficient mice by depletion of regulatory T cells.
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Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses.
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Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses
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Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro.
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Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation.
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Fueling regulation: IL-2 keeps CD4+ Treg cells fit.
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Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
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T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells.
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Regulatory T cells and inflammatory bowel disease.
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OX40 is required for regulatory T cell-mediated control of colitis.
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Immunology. Regulating the regulators.
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Intestinal homeostasis and its breakdown in inflammatory bowel disease.
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Lymphoid microenvironments and innate lymphoid cells in the gut.
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