Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis.
Pseudoporphyria is characterized by erythema, blistering, and scarring on sun-exposed skin. Nonsteroidal antiinflammatory drugs (NSAIDs) are implicated in the etiology of this condition. In a 1-year prospective study of children attending the pediatric rheumatology clinic in Edinburgh we found a pre...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2000
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| _version_ | 1826303833690603520 |
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| author | De Silva, B Banney, L Uttley, W Luqmani, R Schofield, O |
| author_facet | De Silva, B Banney, L Uttley, W Luqmani, R Schofield, O |
| author_sort | De Silva, B |
| collection | OXFORD |
| description | Pseudoporphyria is characterized by erythema, blistering, and scarring on sun-exposed skin. Nonsteroidal antiinflammatory drugs (NSAIDs) are implicated in the etiology of this condition. In a 1-year prospective study of children attending the pediatric rheumatology clinic in Edinburgh we found a prevalence of pseudoporphyria of 10.9% in children taking NSAIDs for juvenile idiopathic arthritis. Naproxen was the most commonly implicated NSAID, independent of dosage. Blue/gray eye color was an independent risk factor for the development of pseudoporphyria. We would advise caution in prescribing naproxen in these children to prevent disfiguring facial scarring. |
| first_indexed | 2024-03-07T06:08:42Z |
| format | Journal article |
| id | oxford-uuid:eeb73dda-ea46-4edd-bc15-c1c570f86d0c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:08:42Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:eeb73dda-ea46-4edd-bc15-c1c570f86d0c2022-03-27T11:34:58ZPseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eeb73dda-ea46-4edd-bc15-c1c570f86d0cEnglishSymplectic Elements at Oxford2000De Silva, BBanney, LUttley, WLuqmani, RSchofield, OPseudoporphyria is characterized by erythema, blistering, and scarring on sun-exposed skin. Nonsteroidal antiinflammatory drugs (NSAIDs) are implicated in the etiology of this condition. In a 1-year prospective study of children attending the pediatric rheumatology clinic in Edinburgh we found a prevalence of pseudoporphyria of 10.9% in children taking NSAIDs for juvenile idiopathic arthritis. Naproxen was the most commonly implicated NSAID, independent of dosage. Blue/gray eye color was an independent risk factor for the development of pseudoporphyria. We would advise caution in prescribing naproxen in these children to prevent disfiguring facial scarring. |
| spellingShingle | De Silva, B Banney, L Uttley, W Luqmani, R Schofield, O Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis. |
| title | Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis. |
| title_full | Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis. |
| title_fullStr | Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis. |
| title_full_unstemmed | Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis. |
| title_short | Pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis. |
| title_sort | pseudoporphyria and nonsteroidal antiinflammatory agents in children with juvenile idiopathic arthritis |
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