Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk.

Functional single nucleotide polymorphisms within the cyclin-dependent kinase inhibitor 2A/2B region affect pancreatic cancer risk.

The CDKN2A(p16) gene plays a key role in pancreatic cancer etiology. It is one of the most commonly somatically mutated genes in pancreatic cancer, rare germline mutations have been found to be associated with increased risk of developing familiar pancreatic cancer and CDKN2A promoter hyper-methylat...

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Main Authors: Campa, D, Pastore, M, Gentiluomo, M, Talar-Wojnarowska, R, Kupcinskas, J, Malecka-Panas, E, Neoptolemos, J, Niesen, W, Vodicka, P, Delle Fave, G, Bas Bueno-de-Mesquita, H, Gazouli, M, Pacetti, P, Di Leo, M, Ito, H, Klüter, H, Soucek, P, Corbo, V, Yamao, K, Hosono, S, Kaaks, R, Vashist, Y, Gioffreda, D, Strobel, O, Shimizu, Y, Dijk, F, Andriulli, A, Ivanauskas, A, Bugert, P, Tavano, F, Vodickova, L, Federico Zambon, C, Lovecek, M, Landi, S, Key, T, Boggi, U, Pezzilli, R, Jamroziak, K, Mohelnikova-Duchonova, B, Mambrini, A, Bambi, F, Busch, O, Pazienza, V, Valente, R, Theodoropoulos, G, Hackert, T, Capurso, G, Martina Cavestro, G, Pasquali, C, Basso, D, Sperti, C, Matsuo, K, Büchler, M, Khaw, K, Izbicki, J, Costello, E, Katzke, V, Michalski, C, Stepien, A, Rizzato, C, Canzian, F
Format: Journal article
Language:English
Published: Impact Journals 2016

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