Dystrophin and utrophin are functionally homologous actin binding proteins but act through distinct modes of filament association

Dystrophin and utrophin are functionally homologous actin binding proteins but act through distinct modes of filament association

Bibliographic Details
Main Authors:	Rybakova, I, Patel, JR, Davies, K, Yurchenco, P, Ervasti, J
Format:	Journal article
Published:	2001

Similar Items

Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle.
by: Rybakova, I, et al.
Published: (2002)

Functional substitution by TAT-utrophin in dystrophin-deficient mice.
by: Kevin J Sonnemann, et al.
Published: (2009-05-01)

ZZ domain is essentially required for the physiological binding of dystrophin and utrophin to beta-dystroglycan.
by: Ishikawa-Sakurai, M, et al.
Published: (2004)

The utrophin and dystrophin genes share similarities in genomic structure.
by: Pearce, M, et al.
Published: (1993)

Immunogold confirmation that utrophin is localized to the normal position of dystrophin in dystrophin-negative transgenic mouse muscle.
by: Culle, M, et al.
Published: (2001)

The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy
by: Guiraud, S, et al.
Published: (2019)

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.
by: Wakefield, P, et al.
Published: (2000)

Confirmation by immunogold labeling that utrophin is localised to the normal position of dystrophin in dystrophin-negative transgenic mouse muscle
by: Cullen, M, et al.
Published: (2001)

Generation of clusters of dystrophin revertant fibers requires muscle regeneration and tests the function of dystrophin/utrophin transgenes
by: Yokota, T, et al.
Published: (2004)

Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis
by: Hung-Chih Chen, et al.
Published: (2017-08-01)

A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.
by: Cole, M, et al.
Published: (2002)

Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.
by: Griffin, J, et al.
Published: (2002)

Dystrophin and utrophin influence fiber type composition and post-synaptic membrane structure.
by: Rafael, J, et al.
Published: (2000)

Tissue-Specificity of Dystrophin–Actin Interactions: Isoform-Specific Thermodynamic Stability and Actin-Binding Function of Tandem Calponin-Homology Domains
by: Vaibhav Upadhyay, et al.
Published: (2020-01-01)

Microarray analysis of mdx mice expressing high levels of utrophin: therapeutic implications for dystrophin deficiency.
by: Baban, D, et al.
Published: (2008)

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.
by: Li, D, et al.
Published: (2010)

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin
by: Li, D, et al.
Published: (2010)

Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice.
by: Dejia Li, et al.
Published: (2010-12-01)

Rescu of severely affected dystrophin/utrophin deficient mice by morpholino-oligomer mediated exon skipping
by: Goyenvalle, A, et al.
Published: (2010)

Promising therapeutic approaches of utrophin replacing dystrophin in the treatment of Duchenne muscular dystrophy
by: Ruo Wu, et al.
Published: (2022-11-01)

Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy
by: Perkins, K, et al.
Published: (2018)

Prevention of dystrophic pathology in severely affected dystrophin/utrophin-deficient mice by morpholino-oligomer-mediated exon-skipping.
by: Goyenvalle, A, et al.
Published: (2010)

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
by: Hanson, B, et al.
Published: (2022)

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
by: Britt Hanson, et al.
Published: (2022-12-01)

Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice
by: Daniel J. Ham, et al.
Published: (2019-09-01)

Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity
by: Justin P. Hardee, et al.
Published: (2021-03-01)

Correlation of utrophin levels with the dystrophin protein complex and muscle fibre regeneration in Duchenne and Becker muscular dystrophy muscle biopsies
by: Janghra, N, et al.
Published: (2016)

Biased localization of actin binding proteins by actin filament conformation
by: Andrew R. Harris, et al.
Published: (2020-11-01)

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.
by: Narinder Janghra, et al.
Published: (2016-01-01)

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.
by: Meghna Pant, et al.
Published: (2015-01-01)

Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.
by: Nakamura, A, et al.
Published: (2001)

Direct Visualization of Actin Filaments and Actin-Binding Proteins in Neuronal Cells
by: Minkyo Jung, et al.
Published: (2020-11-01)

Calponin-homology domain mediated bending of membrane-associated actin filaments
by: Saravanan Palani, et al.
Published: (2021-07-01)

Distinct Relations of Microtubules and Actin Filaments with Dendritic Architecture
by: Sumit Nanda, et al.
Published: (2020-12-01)

Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.
by: Moghadaszadeh, B, et al.
Published: (2003)

Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping
by: Goyenvalle, A, et al.
Published: (2012)

Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.
by: Goyenvalle, A, et al.
Published: (2012)

Actin-binding domains mediate the distinct distribution of two Dictyostelium Talins through different affinities to specific subsets of actin filaments during directed cell migration.
by: Masatsune Tsujioka, et al.
Published: (2019-01-01)

A and B utrophin in human muscle and sarcolemmal A-utrophin associated with tumours.
by: Sewry, C, et al.
Published: (2005)

A peek into tropomyosin binding and unfolding on the actin filament.
by: Abhishek Singh, et al.
Published: (2009-07-01)