Retinal changes in visceral leishmaniasis by retinal photography
<p style="text-align:justify;"> <b>Background:</b> In visceral leishmaniasis (VL), retinal changes have previously been noted but not described in detail and their clinical and pathological significance are unknown. A prospective observational study was undertaken in Mym...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
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BioMed Central
2014
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| _version_ | 1826303869053829120 |
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| author | Maude, R Ahmed, B Rahman, A Rahman, R Majumder, M Menezes, D Abu Sayeed, A Hughes, L Macgillivray, T Borooah, S Dhillon, B Dondorp, A Faiz, M |
| author_facet | Maude, R Ahmed, B Rahman, A Rahman, R Majumder, M Menezes, D Abu Sayeed, A Hughes, L Macgillivray, T Borooah, S Dhillon, B Dondorp, A Faiz, M |
| author_sort | Maude, R |
| collection | OXFORD |
| description | <p style="text-align:justify;"> <b>Background:</b> In visceral leishmaniasis (VL), retinal changes have previously been noted but not described in detail and their clinical and pathological significance are unknown. A prospective observational study was undertaken in Mymensingh, Bangladesh aiming to describe in detail visible changes in the retina in unselected patients with VL.<br/><br/> <b>Methods:</b> Patients underwent assessment of visual function, indirect and direct ophthalmoscopy and portable retinal photography. The photographs were assessed by masked observers including assessment for vessel tortuosity using a semi-automated system.<br/><br/> <b>Results:</b> 30 patients with VL were enrolled, of whom 6 (20%) had abnormalities. These included 5 with focal retinal whitening, 2 with cotton wool spots, 2 with haemorrhages, as well as increased vessel tortuosity. Visual function was preserved.<br/><br/> <b>Conclusions:</b> These changes suggest a previously unrecognized retinal vasculopathy. An inflammatory aetiology is plausible such as a subclinical retinal vasculitis, possibly with altered local microvascular autoregulation, and warrants further investigation. </p> |
| first_indexed | 2024-03-07T06:09:14Z |
| format | Journal article |
| id | oxford-uuid:eee7a83b-1a85-429d-a3b4-ecc14ba2c4ab |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:09:14Z |
| publishDate | 2014 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:eee7a83b-1a85-429d-a3b4-ecc14ba2c4ab2022-03-27T11:36:20ZRetinal changes in visceral leishmaniasis by retinal photographyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eee7a83b-1a85-429d-a3b4-ecc14ba2c4abEnglishSymplectic Elements at OxfordBioMed Central2014Maude, RAhmed, BRahman, ARahman, RMajumder, MMenezes, DAbu Sayeed, AHughes, LMacgillivray, TBorooah, SDhillon, BDondorp, AFaiz, M <p style="text-align:justify;"> <b>Background:</b> In visceral leishmaniasis (VL), retinal changes have previously been noted but not described in detail and their clinical and pathological significance are unknown. A prospective observational study was undertaken in Mymensingh, Bangladesh aiming to describe in detail visible changes in the retina in unselected patients with VL.<br/><br/> <b>Methods:</b> Patients underwent assessment of visual function, indirect and direct ophthalmoscopy and portable retinal photography. The photographs were assessed by masked observers including assessment for vessel tortuosity using a semi-automated system.<br/><br/> <b>Results:</b> 30 patients with VL were enrolled, of whom 6 (20%) had abnormalities. These included 5 with focal retinal whitening, 2 with cotton wool spots, 2 with haemorrhages, as well as increased vessel tortuosity. Visual function was preserved.<br/><br/> <b>Conclusions:</b> These changes suggest a previously unrecognized retinal vasculopathy. An inflammatory aetiology is plausible such as a subclinical retinal vasculitis, possibly with altered local microvascular autoregulation, and warrants further investigation. </p> |
| spellingShingle | Maude, R Ahmed, B Rahman, A Rahman, R Majumder, M Menezes, D Abu Sayeed, A Hughes, L Macgillivray, T Borooah, S Dhillon, B Dondorp, A Faiz, M Retinal changes in visceral leishmaniasis by retinal photography |
| title | Retinal changes in visceral leishmaniasis by retinal photography |
| title_full | Retinal changes in visceral leishmaniasis by retinal photography |
| title_fullStr | Retinal changes in visceral leishmaniasis by retinal photography |
| title_full_unstemmed | Retinal changes in visceral leishmaniasis by retinal photography |
| title_short | Retinal changes in visceral leishmaniasis by retinal photography |
| title_sort | retinal changes in visceral leishmaniasis by retinal photography |
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