Transcription initiation activity sets replication origin efficiency in mammalian cells.
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory complexity of our genome. Here we combine a genome-wide approach to identify preferential sites of DNA replication initiation at 0.4% of the mouse genome with detailed molecular an...
Main Authors: | Sequeira-Mendes, J, Diaz-Uriarte, R, Apedaile, A, Huntley, D, Brockdorff, N, Gomez, M |
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格式: | Journal article |
語言: | English |
出版: |
Public Library of Science
2009
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