Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis.

Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis.

OBJECTIVE: IL-23 is a pro-inflammatory cytokine proposed to be central to the development of autoimmune disease. We investigated whether IL-23, together with the downstream mediator IL-17A, was present and functional in RA in humans. METHODS: RA synovial cells were cultured in the presence or absen...

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Détails bibliographiques
Auteurs principaux:	Hillyer, P, Larché, M, Bowman, E, McClanahan, T, de Waal Malefyt, R, Schewitz, L, Giddins, G, Feldmann, M, Kastelein, R, Brennan, F
Format:	Journal article
Langue:	English
Publié:	2009

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