Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride

<p>Herein, we report the radiosynthesis of <sup>18</sup>F-difluoromethylarenes <italic>via</italic> the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [<sup>18</sup>F]fluoride.</p>

Bibliographic Details
Main Authors: Sap, J, Wilson, T, Kee, C, Straathof, N, Ende, C, Mukherjee, P, Zhang, L, Genicot, C, Gouverneur, V
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2019
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author Sap, J
Wilson, T
Kee, C
Straathof, N
Ende, C
Mukherjee, P
Zhang, L
Genicot, C
Gouverneur, V
author_facet Sap, J
Wilson, T
Kee, C
Straathof, N
Ende, C
Mukherjee, P
Zhang, L
Genicot, C
Gouverneur, V
author_sort Sap, J
collection OXFORD
description <p>Herein, we report the radiosynthesis of <sup>18</sup>F-difluoromethylarenes <italic>via</italic> the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [<sup>18</sup>F]fluoride.</p>
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spelling oxford-uuid:ef33137e-73ab-49f9-8eeb-26880d0a170e2022-03-27T11:38:33ZSynthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluorideJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ef33137e-73ab-49f9-8eeb-26880d0a170eEnglishSymplectic Elements at OxfordRoyal Society of Chemistry2019Sap, JWilson, TKee, CStraathof, NEnde, CMukherjee, PZhang, LGenicot, CGouverneur, V<p>Herein, we report the radiosynthesis of <sup>18</sup>F-difluoromethylarenes <italic>via</italic> the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [<sup>18</sup>F]fluoride.</p>
spellingShingle Sap, J
Wilson, T
Kee, C
Straathof, N
Ende, C
Mukherjee, P
Zhang, L
Genicot, C
Gouverneur, V
Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
title Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
title_full Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
title_fullStr Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
title_full_unstemmed Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
title_short Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
title_sort synthesis of 18f difluoromethylarenes using aryl boronic acids ethyl bromofluoroacetate and 18f fluoride
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AT keec synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride
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