Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride
<p>Herein, we report the radiosynthesis of <sup>18</sup>F-difluoromethylarenes <italic>via</italic> the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [<sup>18</sup>F]fluoride.</p>
Main Authors: | , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Royal Society of Chemistry
2019
|
_version_ | 1797102744375394304 |
---|---|
author | Sap, J Wilson, T Kee, C Straathof, N Ende, C Mukherjee, P Zhang, L Genicot, C Gouverneur, V |
author_facet | Sap, J Wilson, T Kee, C Straathof, N Ende, C Mukherjee, P Zhang, L Genicot, C Gouverneur, V |
author_sort | Sap, J |
collection | OXFORD |
description | <p>Herein, we report the radiosynthesis of <sup>18</sup>F-difluoromethylarenes <italic>via</italic> the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [<sup>18</sup>F]fluoride.</p> |
first_indexed | 2024-03-07T06:10:09Z |
format | Journal article |
id | oxford-uuid:ef33137e-73ab-49f9-8eeb-26880d0a170e |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T06:10:09Z |
publishDate | 2019 |
publisher | Royal Society of Chemistry |
record_format | dspace |
spelling | oxford-uuid:ef33137e-73ab-49f9-8eeb-26880d0a170e2022-03-27T11:38:33ZSynthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluorideJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ef33137e-73ab-49f9-8eeb-26880d0a170eEnglishSymplectic Elements at OxfordRoyal Society of Chemistry2019Sap, JWilson, TKee, CStraathof, NEnde, CMukherjee, PZhang, LGenicot, CGouverneur, V<p>Herein, we report the radiosynthesis of <sup>18</sup>F-difluoromethylarenes <italic>via</italic> the assembly of three components, a boron reagent, ethyl bromofluoroacetate, and cyclotron-produced non-carrier added [<sup>18</sup>F]fluoride.</p> |
spellingShingle | Sap, J Wilson, T Kee, C Straathof, N Ende, C Mukherjee, P Zhang, L Genicot, C Gouverneur, V Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride |
title | Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride |
title_full | Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride |
title_fullStr | Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride |
title_full_unstemmed | Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride |
title_short | Synthesis of 18F-difluoromethylarenes using aryl boronic acids, ethyl bromofluoroacetate and [18F]fluoride |
title_sort | synthesis of 18f difluoromethylarenes using aryl boronic acids ethyl bromofluoroacetate and 18f fluoride |
work_keys_str_mv | AT sapj synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT wilsont synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT keec synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT straathofn synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT endec synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT mukherjeep synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT zhangl synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT genicotc synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride AT gouverneurv synthesisof18fdifluoromethylarenesusingarylboronicacidsethylbromofluoroacetateand18ffluoride |