Therapy with monoclonal antibodies. An in vivo model for the assessment of therapeutic potential.

Therapy with monoclonal antibodies. An in vivo model for the assessment of therapeutic potential.

A set of rat-human and rat-rat chimeric mAb has been created, all possessing V regions identical in their specificity for the mouse CD8 Ag. In vitro all antibodies were able to block cell-mediated lysis but varied greatly in their capacity to utilize rabbit complement. We examined the ability of the...

Bibliografiset tiedot
Päätekijät:	Isaacs, J, Clark, MR, Greenwood, J, Waldmann, H
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	1992

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