Investigating the role of IGF-1R in radio-sensitivity

The insulin-like growth factor (IGF) axis is an important regulator of cancer cell proliferation, growth, invasion, and can also mediate therapy resistance. Inhibition or depletion of the type 1 IGF receptor (IGF-1R) has been shown by our laboratory and others to enhance sensitivity to ionising radi...

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Bibliographic Details
Main Author: Ellis, M
Other Authors: Macaulay, V
Format: Thesis
Language:English
Published: 2020
Subjects:

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