Investigating the role of IGF-1R in radio-sensitivity
The insulin-like growth factor (IGF) axis is an important regulator of cancer cell proliferation, growth, invasion, and can also mediate therapy resistance. Inhibition or depletion of the type 1 IGF receptor (IGF-1R) has been shown by our laboratory and others to enhance sensitivity to ionising radi...
Main Author: | Ellis, M |
---|---|
Other Authors: | Macaulay, V |
Format: | Thesis |
Language: | English |
Published: |
2020
|
Subjects: |
Similar Items
-
Melatonin as a Radio-Sensitizer in Cancer
by: Carolina Alonso-González, et al.
Published: (2020-07-01) -
CRISPR-Cas9 Screen Identifies DYRK1A as a Target for Radiotherapy Sensitization in Pancreatic Cancer
by: Bin Lan, et al.
Published: (2022-01-01) -
Investigation of haematopoietic cell growth and the impact of common mutations in myeloid malignancies
by: Tittrea, V
Published: (2021) -
Curcumin enhances the radio-sensitivity of prostate cancer cell line PC-3
by: CHENG Ji, FU Guo, ZHAO Hua-cai, WANG Zhi-gang, GAO Dan, DONG Qing-chuan
Published: (2021-12-01) -
GIGYF1 disruption associates with autism and impaired IGF-1R signaling
by: Guodong Chen, et al.
Published: (2022-10-01)