Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.

T-cell production throughout life depends on efficient colonization and intrathymic expansion of BM-derived hematopoietic precursors. After irradiation-induced thymic damage, thymic recovery is facilitated by Flt3 ligand (FL), expressed by perivascular fibroblasts surrounding the thymic entry site o...

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書目詳細資料
Main Authors: Kenins, L, Gill, J, Holländer, G, Wodnar-Filipowicz, A
格式: Journal article
語言:English
出版: 2010

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