Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis.
T-cell production throughout life depends on efficient colonization and intrathymic expansion of BM-derived hematopoietic precursors. After irradiation-induced thymic damage, thymic recovery is facilitated by Flt3 ligand (FL), expressed by perivascular fibroblasts surrounding the thymic entry site o...
Main Authors: | Kenins, L, Gill, J, Holländer, G, Wodnar-Filipowicz, A |
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格式: | Journal article |
語言: | English |
出版: |
2010
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