Allele-specific gene expression uncovered.

Genetic variation in populations can result in variation in levels of gene expression but the extent to which this occurs has been unclear. In this article, recent studies of allele-specific expression among autosomal non-imprinted genes are reviewed. These new data provide evidence that differentia...

Descrición completa

Detalles Bibliográficos
Autor Principal: Knight, J
Formato: Journal article
Idioma:English
Publicado: 2004
Descripción
Summary:Genetic variation in populations can result in variation in levels of gene expression but the extent to which this occurs has been unclear. In this article, recent studies of allele-specific expression among autosomal non-imprinted genes are reviewed. These new data provide evidence that differential expression is relatively common and that allelic differences are heritable and can be highly context specific.