Prophylactic uses of fully reduced forms of hmgb1 prior to injury

The subject invention provides a method of preventing a consequence of an anticipated injury in a subject which comprises administering to the subject a therapeutically effective amount of the fully reduced (all thiol) form of HMGB1 or a biologically active truncated form of HMGB1, so as to prevent...

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Main Authors: Nanchahal, J, Espirito Santo, A, Lee, G, Feldmann, M, Horwood, N
Format: Patent
Language:English
Published: 2019
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author Nanchahal, J
Espirito Santo, A
Lee, G
Feldmann, M
Horwood, N
author_facet Nanchahal, J
Espirito Santo, A
Lee, G
Feldmann, M
Horwood, N
author_sort Nanchahal, J
collection OXFORD
description The subject invention provides a method of preventing a consequence of an anticipated injury in a subject which comprises administering to the subject a therapeutically effective amount of the fully reduced (all thiol) form of HMGB1 or a biologically active truncated form of HMGB1, so as to prevent the consequence of the anticipated injury.
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spelling oxford-uuid:ef6e83bd-b756-44bc-8860-92040425205e2022-03-27T11:40:10ZProphylactic uses of fully reduced forms of hmgb1 prior to injuryPatenthttp://purl.org/coar/resource_type/c_15cduuid:ef6e83bd-b756-44bc-8860-92040425205eEnglishSymplectic Elements2019Nanchahal, JEspirito Santo, ALee, GFeldmann, MHorwood, NThe subject invention provides a method of preventing a consequence of an anticipated injury in a subject which comprises administering to the subject a therapeutically effective amount of the fully reduced (all thiol) form of HMGB1 or a biologically active truncated form of HMGB1, so as to prevent the consequence of the anticipated injury.
spellingShingle Nanchahal, J
Espirito Santo, A
Lee, G
Feldmann, M
Horwood, N
Prophylactic uses of fully reduced forms of hmgb1 prior to injury
title Prophylactic uses of fully reduced forms of hmgb1 prior to injury
title_full Prophylactic uses of fully reduced forms of hmgb1 prior to injury
title_fullStr Prophylactic uses of fully reduced forms of hmgb1 prior to injury
title_full_unstemmed Prophylactic uses of fully reduced forms of hmgb1 prior to injury
title_short Prophylactic uses of fully reduced forms of hmgb1 prior to injury
title_sort prophylactic uses of fully reduced forms of hmgb1 prior to injury
work_keys_str_mv AT nanchahalj prophylacticusesoffullyreducedformsofhmgb1priortoinjury
AT espiritosantoa prophylacticusesoffullyreducedformsofhmgb1priortoinjury
AT leeg prophylacticusesoffullyreducedformsofhmgb1priortoinjury
AT feldmannm prophylacticusesoffullyreducedformsofhmgb1priortoinjury
AT horwoodn prophylacticusesoffullyreducedformsofhmgb1priortoinjury