Recent improvements to the SMART domain-based sequence annotation resource.
SMART (Simple Modular Architecture Research Tool, http://smart.embl-heidelberg.de) is a web-based resource used for the annotation of protein domains and the analysis of domain architectures, with particular emphasis on mobile eukaryotic domains. Extensive annotation for each domain family is availa...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2002
|
| _version_ | 1797102843639889920 |
|---|---|
| author | Letunic, I Goodstadt, L Dickens, N Doerks, T Schultz, J Mott, R Ciccarelli, F Copley, R Ponting, C Bork, P |
| author_facet | Letunic, I Goodstadt, L Dickens, N Doerks, T Schultz, J Mott, R Ciccarelli, F Copley, R Ponting, C Bork, P |
| author_sort | Letunic, I |
| collection | OXFORD |
| description | SMART (Simple Modular Architecture Research Tool, http://smart.embl-heidelberg.de) is a web-based resource used for the annotation of protein domains and the analysis of domain architectures, with particular emphasis on mobile eukaryotic domains. Extensive annotation for each domain family is available, providing information relating to function, subcellular localization, phyletic distribution and tertiary structure. The January 2002 release has added more than 200 hand-curated domain models. This brings the total to over 600 domain families that are widely represented among nuclear, signalling and extracellular proteins. Annotation now includes links to the Online Mendelian Inheritance in Man (OMIM) database in cases where a human disease is associated with one or more mutations in a particular domain. We have implemented new analysis methods and updated others. New advanced queries provide direct access to the SMART relational database using SQL. This database now contains information on intrinsic sequence features such as transmembrane regions, coiled-coils, signal peptides and internal repeats. SMART output can now be easily included in users' documents. A SMART mirror has been created at http://smart.ox.ac.uk. |
| first_indexed | 2024-03-07T06:11:33Z |
| format | Journal article |
| id | oxford-uuid:efae44e6-b4f4-4022-924b-1f052ac4b4a0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:11:33Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:efae44e6-b4f4-4022-924b-1f052ac4b4a02022-03-27T11:42:00ZRecent improvements to the SMART domain-based sequence annotation resource.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:efae44e6-b4f4-4022-924b-1f052ac4b4a0EnglishSymplectic Elements at Oxford2002Letunic, IGoodstadt, LDickens, NDoerks, TSchultz, JMott, RCiccarelli, FCopley, RPonting, CBork, PSMART (Simple Modular Architecture Research Tool, http://smart.embl-heidelberg.de) is a web-based resource used for the annotation of protein domains and the analysis of domain architectures, with particular emphasis on mobile eukaryotic domains. Extensive annotation for each domain family is available, providing information relating to function, subcellular localization, phyletic distribution and tertiary structure. The January 2002 release has added more than 200 hand-curated domain models. This brings the total to over 600 domain families that are widely represented among nuclear, signalling and extracellular proteins. Annotation now includes links to the Online Mendelian Inheritance in Man (OMIM) database in cases where a human disease is associated with one or more mutations in a particular domain. We have implemented new analysis methods and updated others. New advanced queries provide direct access to the SMART relational database using SQL. This database now contains information on intrinsic sequence features such as transmembrane regions, coiled-coils, signal peptides and internal repeats. SMART output can now be easily included in users' documents. A SMART mirror has been created at http://smart.ox.ac.uk. |
| spellingShingle | Letunic, I Goodstadt, L Dickens, N Doerks, T Schultz, J Mott, R Ciccarelli, F Copley, R Ponting, C Bork, P Recent improvements to the SMART domain-based sequence annotation resource. |
| title | Recent improvements to the SMART domain-based sequence annotation resource. |
| title_full | Recent improvements to the SMART domain-based sequence annotation resource. |
| title_fullStr | Recent improvements to the SMART domain-based sequence annotation resource. |
| title_full_unstemmed | Recent improvements to the SMART domain-based sequence annotation resource. |
| title_short | Recent improvements to the SMART domain-based sequence annotation resource. |
| title_sort | recent improvements to the smart domain based sequence annotation resource |
| work_keys_str_mv | AT letunici recentimprovementstothesmartdomainbasedsequenceannotationresource AT goodstadtl recentimprovementstothesmartdomainbasedsequenceannotationresource AT dickensn recentimprovementstothesmartdomainbasedsequenceannotationresource AT doerkst recentimprovementstothesmartdomainbasedsequenceannotationresource AT schultzj recentimprovementstothesmartdomainbasedsequenceannotationresource AT mottr recentimprovementstothesmartdomainbasedsequenceannotationresource AT ciccarellif recentimprovementstothesmartdomainbasedsequenceannotationresource AT copleyr recentimprovementstothesmartdomainbasedsequenceannotationresource AT pontingc recentimprovementstothesmartdomainbasedsequenceannotationresource AT borkp recentimprovementstothesmartdomainbasedsequenceannotationresource |