Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1

Factor H-binding protein (fHbp) is an important meningococcal vaccine antigen. Native outer membrane vesicles with over-expressed fHbp (NOMV OE fHbp) have been shown to induce antibodies with broader functional activity than recombinant fHbp (rfHbp). Improved understanding of this broad coverage wou...

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Váldodahkkit: Marini, A, Rossi, O, Aruta, MG, Micoli, F, Rondini, S, Guadagnuolo, S, Delany, I, Henderson, IR, Cunningham, AF, Saul, A, MacLennan, CA, Koeberling, O
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Public Library of Science 2017

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