Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19
Complement, a critical defence against pathogens, has been implicated as a driver of pathology in COVID-19. Complement activation products are detected in plasma and tissues and complement blockade considered for therapy. To delineate roles of complement in immunopathogenesis, we undertook the large...
| Autori principali: | , , , , , , , , , , |
|---|---|
| Altri autori: | |
| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
Wiley
2022
|