Systems Biology Approach to Drug Development: Application to Toxicity Assessment of Cardiac Drugs
Side effects account for most of the instances of failure of candidate drugs at late stages of development. These development failures contribute to the exorbitant cost of bringing new compounds to market: a single withdrawal can represent a loss of more than 1 billion. Many unwanted actions of drug...
Main Authors: | Rodriguez, B, Burrage, K, Gavaghan, D, Grau, V, Kohl, P, Noble, D |
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Format: | Journal article |
Published: |
2010
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