Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.

Slični predmeti

• Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
  od: Degrève, B, i dr.
  Izdano: (2001)
• The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
  od: Balzarini, J, i dr.
  Izdano: (2002)
• Characterization of multiple nuclear localization signals in herpes simplex virus type 1 thymidine kinase.
  od: Degrève, B, i dr.
  Izdano: (1999)
• Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase.
  od: Balzarini, J, i dr.
  Izdano: (2003)
• Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation.
  od: Balzarini, J, i dr.
  Izdano: (2006)