Host and viral factors that determine the clinical outcome of hepatitis C virus genotype 3a infection

Host and viral factors that determine the clinical outcome of hepatitis C virus genotype 3a infection

<p>HCV infects 170 million persons worldwide and is a serious global health problem. Genotype-3a is the dominant genotype in newly diagnosed infections within the UK and has a high response rate to interferon therapy, with up to 70% patients achieving a sustained virological response (SVR). Th...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Humphreys, I, Isla S. Humphreys
Andre forfattere:	Barnes, E
Format:	Thesis
Sprog:	English
Udgivet:	2011
Fag:	Infectious diseases Biology (medical sciences) Immunology

Lignende værker

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
af: Hennig, B, et al.
Udgivet: (2008)

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C
af: Antrobus, R
Udgivet: (2014)

Use of genome wide expression profiles in analysis of T cell dysfunction in Hepatitis C virus infection
af: Gupta, P
Udgivet: (2014)

Novel adenoviral vectored vaccines and the implications of viral diversity in therapeutic strategies against Hepatitis C Virus infection
af: Kelly, C
Udgivet: (2013)

Aspects to T-cell phenotype during infection with HIV, CMV and Hepatitis C virus
af: Northfield, J
Udgivet: (2008)

Contribution of monocytes to immunopathology during influenza A virus infection
af: Cole, S, et al.
Udgivet: (2014)

Functional impact of CD161 on T cells
af: Smith, K
Udgivet: (2013)

B cell and antibody responses to influenza a virus in human
af: Huang, K
Udgivet: (2011)

mTOR regulates T cell exhaustion and PD-1–targeted immunotherapy response during chronic viral infection
af: Satomi Ando, et al.
Udgivet: (2023-01-01)

The role of the cytoplasmic domain of the macrophage scavenger receptor MARCO in adhesion and uptake
af: Kroos, M
Udgivet: (2008)

Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
af: Ronan, E
Udgivet: (2011)

Understanding the link between interleukin 17 and vaccine-induced protection in tuberculosis
af: Griffiths, K
Udgivet: (2012)

HLA-B51 associated HIV-1 viral control
af: Peng, Y
Udgivet: (2013)

The role of T cell immunity in natural influenza A infection in a UK cohort: flu watch
af: Wang, L
Udgivet: (2014)

Whole-genome sequencing demonstrates that fidaxomicin is superior to vancomycin for preventing reinfection and relapse of infection with Clostridium difficile
af: Eyre, D, et al.
Udgivet: (2013)

Implications of HCV genotype 3 specific immunity on cross-reactive vaccine design
af: von Delft, A, et al.
Udgivet: (2014)

Dynamics of co-infection in fish: A review of pathogen-host interaction and clinical outcome
af: Ekemini Moses Okon, et al.
Udgivet: (2023-12-01)

Variation of HLA class I (-A and -C) genes in individuals infected with hepatitis B or hepatitis C virus in Cameroon
af: Clauvis Kunkeng Yengo, et al.
Udgivet: (2020-10-01)

Liver-stage vaccines for malaria
af: Longley, RJ
Udgivet: (2013)

Function, phenotype and development of human CD161+CD8 T cells
af: Walker, LJ
Udgivet: (2012)

Memory T cell responses in influenza A infection and vaccination in humans
af: Chui, C
Udgivet: (2012)

NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice
af: Ha-Na Lee, et al.
Udgivet: (2022-02-01)

Human papillomavirus type 16 and 18 viral loads as predictors associated with abnormal cervical cytology among women in Saudi Arabia
af: D.A. Obeid, et al.
Udgivet: (2020-02-01)

Hepatitis B vaccination
af: Pollard, A
Udgivet: (2007)

Mycobacterium tuberculosis hijacks host TRIM21- and NCOA4-dependent ferritinophagy to enhance intracellular growth
af: Youchao Dai, et al.
Udgivet: (2023-04-01)

IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice
af: Prashant Rai, et al.
Udgivet: (2023-11-01)

Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections
af: Simone A. Thair, et al.
Udgivet: (2021-01-01)

A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion
af: Horton, Brendan, et al.
Udgivet: (2020)

Longitudinal liver sampling in patients with chronic hepatitis B starting antiviral therapy reveals hepatotoxic CD8+ T cells
af: Shirin Nkongolo, et al.
Udgivet: (2023-01-01)

Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses
af: Laura K. Aisenberg, et al.
Udgivet: (2022-06-01)

Immunopathogenic CSF TCR repertoire signatures in virus-associated neurologic disease
af: Satoshi Nozuma, et al.
Udgivet: (2021-02-01)

Characterisation of expression and function of respiratory epithelial CD1d
af: Hajipouran Benam, K
Udgivet: (2014)

Potently neutralizing human mAbs against the zoonotic pararubulavirus Sosuga virus
af: Helen M. Parrington, et al.
Udgivet: (2023-04-01)

Characterisation of the immune response to PARV4
af: Simmons, RA
Udgivet: (2011)

Protocol for influenza A virus infection of mice and viral load determination
af: Ioanna-Evdokia Galani, et al.
Udgivet: (2022-03-01)

Transcutaneous delivery of T Cell-inducing viral vector Malaria vaccines by microneedle patches
af: Pearson, FE
Udgivet: (2011)

Hepatitis C virus hypervariable region 1 antibodies interrupt E2-SR-B1 interaction to suppress viral infection
af: Kai Deng, et al.
Udgivet: (2023-04-01)

Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection
af: Juan-Manuel Leyva-Castillo, et al.
Udgivet: (2021-11-01)

Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells
af: Hung Le, et al.
Udgivet: (2022-08-01)

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses
af: McNaughton, AL, et al.
Udgivet: (2022)