TDP-43 based biomarker development in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease which is clinically and aetiologically heterogenous. However, TDP-43 neuropathology is a unifying hallmark found in 97% of ALS cases. Understanding the common pathological pathways downstream of TDP-43 dysregulation is essentia...
Autore principale: | |
---|---|
Altri autori: | |
Natura: | Tesi |
Lingua: | English |
Pubblicazione: |
2019
|
Soggetti: |