TDP-43 based biomarker development in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease which is clinically and aetiologically heterogenous. However, TDP-43 neuropathology is a unifying hallmark found in 97% of ALS cases. Understanding the common pathological pathways downstream of TDP-43 dysregulation is essentia...
Autore principale: | Feneberg, E |
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Altri autori: | Turner, M |
Natura: | Tesi |
Lingua: | English |
Pubblicazione: |
2019
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Soggetti: |
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