TDP-43 based biomarker development in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease which is clinically and aetiologically heterogenous. However, TDP-43 neuropathology is a unifying hallmark found in 97% of ALS cases. Understanding the common pathological pathways downstream of TDP-43 dysregulation is essentia...

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Detalles Bibliográficos
Autor Principal: Feneberg, E
Outros autores: Turner, M
Formato: Thesis
Idioma:English
Publicado: 2019
Subjects: