Lobeline for smoking cessation.
BACKGROUND: Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES: The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH METHODS: We searched the Cochrane T...
| Prif Awduron: | , |
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| Fformat: | Journal article |
| Iaith: | English |
| Cyhoeddwyd: |
2012
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| _version_ | 1826304089476038656 |
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| author | Stead, L Hughes, JR |
| author_facet | Stead, L Hughes, JR |
| author_sort | Stead, L |
| collection | OXFORD |
| description | BACKGROUND: Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES: The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH METHODS: We searched the Cochrane Tobacco Addiction Group trials register (most recent search December 2011). SELECTION CRITERIA: Randomized trials comparing lobeline to placebo or an alternative therapeutic control, which reported smoking cessation with at least six months follow-up. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the type of subjects, the dose and form of lobeline, the outcome measures, method of randomisation, and completeness of follow-up. MAIN RESULTS: We identified no trials meeting the full inclusion criteria including long term follow-up. One large trial failed to detect any effect on short-term abstinence. AUTHORS' CONCLUSIONS: There is no evidence available from long term trials that lobeline can aid smoking cessation, and the short-term evidence suggests there is no benefit. |
| first_indexed | 2024-03-07T06:12:30Z |
| format | Journal article |
| id | oxford-uuid:f0041532-8da3-40a1-80cb-cb420c54e27f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T06:12:30Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:f0041532-8da3-40a1-80cb-cb420c54e27f2022-03-27T11:44:26ZLobeline for smoking cessation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f0041532-8da3-40a1-80cb-cb420c54e27fEnglishSymplectic Elements at Oxford2012Stead, LHughes, JR BACKGROUND: Lobeline is a partial nicotine agonist, which has been used in a variety of commercially available preparations to help stop smoking. OBJECTIVES: The objective of this review was to assess the effects of lobeline on long term smoking cessation. SEARCH METHODS: We searched the Cochrane Tobacco Addiction Group trials register (most recent search December 2011). SELECTION CRITERIA: Randomized trials comparing lobeline to placebo or an alternative therapeutic control, which reported smoking cessation with at least six months follow-up. DATA COLLECTION AND ANALYSIS: We extracted data in duplicate on the type of subjects, the dose and form of lobeline, the outcome measures, method of randomisation, and completeness of follow-up. MAIN RESULTS: We identified no trials meeting the full inclusion criteria including long term follow-up. One large trial failed to detect any effect on short-term abstinence. AUTHORS' CONCLUSIONS: There is no evidence available from long term trials that lobeline can aid smoking cessation, and the short-term evidence suggests there is no benefit. |
| spellingShingle | Stead, L Hughes, JR Lobeline for smoking cessation. |
| title | Lobeline for smoking cessation. |
| title_full | Lobeline for smoking cessation. |
| title_fullStr | Lobeline for smoking cessation. |
| title_full_unstemmed | Lobeline for smoking cessation. |
| title_short | Lobeline for smoking cessation. |
| title_sort | lobeline for smoking cessation |
| work_keys_str_mv | AT steadl lobelineforsmokingcessation AT hughesjr lobelineforsmokingcessation |