Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.

A genome-wide association scan in individuals with Crohn's disease by the Wellcome Trust Case Control Consortium detected strong association at four novel loci. We tested 37 SNPs from these and other loci for association in an independent case-control sample. We obtained replication for the aut...

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Hlavní autoři:	Parkes, M, Barrett, J, Prescott, N, Tremelling, M, Anderson, C, Fisher, SA, Roberts, R, Nimmo, E, Cummings, F, Soars, D, Drummond, H, Lees, C, Khawaja, SA, Bagnall, R, Burke, D, Todhunter, C, Ahmad, T, Onnie, C, McArdle, W, Strachan, D, Bethel, G, Bryan, C, Lewis, C, Deloukas, P, Forbes, A
Médium:	Journal article
Jazyk:	English
Vydáno:	2007

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.

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