Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction.

The mechanical properties of the extracellular matrix have recently been shown to promote myofibroblast differentiation and lung fibrosis. Mechanisms by which matrix stiffness regulates myofibroblast differentiation are not fully understood. The goal of this study was to determine the intrinsic mech...

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Bibliografiska uppgifter
Huvudupphovsmän: Huang, X, Yang, N, Fiore, V, Barker, T, Sun, Y, Morris, S, Ding, Q, Thannickal, V, Zhou, Y
Materialtyp: Journal article
Språk:English
Publicerad: 2012