Folding of apocytochrome c in lipid micelles: formation of alpha-helix precedes membrane insertion.

Apocytochrome c, which in aqueous solution is largely unstructured, acquires a highly alpha-helical structure upon interaction with lipid. The alpha-helix content induced in apocytochrome c depends on the lipid system, and this folding process is driven by both electrostatic and hydrophobic lipid-pr...

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Bibliographic Details
Main Authors: Bryson, E, Rankin, SE, Carey, M, Watts, A, Pinheiro, T
Format: Journal article
Language:English
Published: 1999