Comparison of thymocyte development in normal and invariant chain-deficient mice provides evidence that maturation-related changes in TCR and co-receptor levels play a critical role in cell fate.

Comparison of thymocyte development in normal and invariant chain-deficient mice provides evidence that maturation-related changes in TCR and co-receptor levels play a critical role in cell fate.

Cells of invariant chain-deficient mice show a substantial decrease in cell surface MHC class II protein expression, as well as a change in the occupancy of the expressed class II molecules. Taking advantage of recent advances in phenotypic identification of transitional populations of developing th...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Huang, L, van Meerwijk, J, Bikoff, E, Germain, R
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	1996

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