Tolerance to rat monoclonal antibodies. Implications for serotherapy.
The antiglobulin response is a major complication of mAb therapy. It has been suggested that, in clinical practice, this might be avoided by using human or chimeric mAbs, or by prior induction of tolerance to the therapeutic mAb. In this study, we show that it is possible to induce tolerance in mice...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
1986
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