Postprandial lipoprotein metabolism and atherosclerosis.

Postprandial lipids and lipoproteins have been associated with the presence of cardiovascular disease in a large number of case-control studies. Because the metabolic perturbations around the postprandial situation is a key driving force for cholesterol flux between lipoproteins and tissues, togethe...

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Autore principale: Karpe, F
Natura: Journal article
Lingua:English
Pubblicazione: 1999
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author Karpe, F
author_facet Karpe, F
author_sort Karpe, F
collection OXFORD
description Postprandial lipids and lipoproteins have been associated with the presence of cardiovascular disease in a large number of case-control studies. Because the metabolic perturbations around the postprandial situation is a key driving force for cholesterol flux between lipoproteins and tissues, together with the augmented generation of potentially atherogenic cholesterol-rich remnant lipoproteins, several hypotheses have been formulated to link excessive lipoproteinaemic response to fat intake with cardiovascular disease. Recent information on the regulation of lipoprotein remnant formation and its relation to atherosclerosis will enable us to test a pertinent clinical question: is there a direct relationship between repeated elevations of postprandial lipoproteins and development of atherosclerosis?
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spelling oxford-uuid:f07fb4ff-8231-4eb3-b215-2a490bf1d3a82022-03-27T11:48:23ZPostprandial lipoprotein metabolism and atherosclerosis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f07fb4ff-8231-4eb3-b215-2a490bf1d3a8EnglishSymplectic Elements at Oxford1999Karpe, FPostprandial lipids and lipoproteins have been associated with the presence of cardiovascular disease in a large number of case-control studies. Because the metabolic perturbations around the postprandial situation is a key driving force for cholesterol flux between lipoproteins and tissues, together with the augmented generation of potentially atherogenic cholesterol-rich remnant lipoproteins, several hypotheses have been formulated to link excessive lipoproteinaemic response to fat intake with cardiovascular disease. Recent information on the regulation of lipoprotein remnant formation and its relation to atherosclerosis will enable us to test a pertinent clinical question: is there a direct relationship between repeated elevations of postprandial lipoproteins and development of atherosclerosis?
spellingShingle Karpe, F
Postprandial lipoprotein metabolism and atherosclerosis.
title Postprandial lipoprotein metabolism and atherosclerosis.
title_full Postprandial lipoprotein metabolism and atherosclerosis.
title_fullStr Postprandial lipoprotein metabolism and atherosclerosis.
title_full_unstemmed Postprandial lipoprotein metabolism and atherosclerosis.
title_short Postprandial lipoprotein metabolism and atherosclerosis.
title_sort postprandial lipoprotein metabolism and atherosclerosis
work_keys_str_mv AT karpef postprandiallipoproteinmetabolismandatherosclerosis