Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping

Fluorescent photon scattering is known to distort optical recordings of cardiac transmembrane potentials; however, this process is not well quantified, hampering interpretation of experimental data. This study presents a novel model, which accurately synthesizes fluorescent recordings over the irreg...

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Main Authors: Bishop, M, Rodriguez, B, Eason, J, Whiteley, J, Trayanova, N, Gavaghan, D
Format: Journal article
Published: 2006
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author Bishop, M
Rodriguez, B
Eason, J
Whiteley, J
Trayanova, N
Gavaghan, D
author_facet Bishop, M
Rodriguez, B
Eason, J
Whiteley, J
Trayanova, N
Gavaghan, D
author_sort Bishop, M
collection OXFORD
description Fluorescent photon scattering is known to distort optical recordings of cardiac transmembrane potentials; however, this process is not well quantified, hampering interpretation of experimental data. This study presents a novel model, which accurately synthesizes fluorescent recordings over the irregular geometry of the rabbit ventricles. Using the model, the study aims to provide quantification of fluorescent signal distortion for different optical characteristics of the preparation and of the surrounding
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institution University of Oxford
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spelling oxford-uuid:f0cba44f-020a-48c7-badb-1afebc95f31b2022-03-27T11:50:56ZSynthesis of voltage−sensitive optical signals: Application to panoramic optical mappingJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f0cba44f-020a-48c7-badb-1afebc95f31bDepartment of Computer Science2006Bishop, MRodriguez, BEason, JWhiteley, JTrayanova, NGavaghan, DFluorescent photon scattering is known to distort optical recordings of cardiac transmembrane potentials; however, this process is not well quantified, hampering interpretation of experimental data. This study presents a novel model, which accurately synthesizes fluorescent recordings over the irregular geometry of the rabbit ventricles. Using the model, the study aims to provide quantification of fluorescent signal distortion for different optical characteristics of the preparation and of the surrounding
spellingShingle Bishop, M
Rodriguez, B
Eason, J
Whiteley, J
Trayanova, N
Gavaghan, D
Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping
title Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping
title_full Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping
title_fullStr Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping
title_full_unstemmed Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping
title_short Synthesis of voltage−sensitive optical signals: Application to panoramic optical mapping
title_sort synthesis of voltage sensitive optical signals application to panoramic optical mapping
work_keys_str_mv AT bishopm synthesisofvoltagesensitiveopticalsignalsapplicationtopanoramicopticalmapping
AT rodriguezb synthesisofvoltagesensitiveopticalsignalsapplicationtopanoramicopticalmapping
AT easonj synthesisofvoltagesensitiveopticalsignalsapplicationtopanoramicopticalmapping
AT whiteleyj synthesisofvoltagesensitiveopticalsignalsapplicationtopanoramicopticalmapping
AT trayanovan synthesisofvoltagesensitiveopticalsignalsapplicationtopanoramicopticalmapping
AT gavaghand synthesisofvoltagesensitiveopticalsignalsapplicationtopanoramicopticalmapping