The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein

The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein

The hepatitis C virus (HCV) encodes the p7 protein that oligomerizes to form an ion channel. The 63 amino acid long p7 monomer is an integral membrane protein predominantly found in the endoplasmic reticulum (ER). Although it is currently unknown whether p7 is incorporated into secreted virions, its...

書誌詳細
主要な著者:	Whitfield, T, Miles, A, Scheinost, J, Offer, J, Wentworth, P, Dwek, R, Wallace, B, Biggin, P, Zitzmann, N
フォーマット:	Journal article
言語:	English
出版事項:	Taylor and Francis 2011

類似資料

The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy.
著者:: Luik, P, 等
出版事項: (2009)

Protein-protein interactions: modeling the hepatitis C virus ion channel p7.
著者:: Patargias, G, 等
出版事項: (2005)

The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives.
著者:: Pavlović, D, 等
出版事項: (2003)

Deciphering the Relationship Between Hepatitis C Virus (HCV) P7 and Its Foes
著者:: Chew, C, 等
出版事項: (2010)

Use of iminosugar derivatives to inhibit ion channel activity
著者:: Zitzmann, N, 等
出版事項: (2004)

Determination of pore-lining residues in the hepatitis C virus p7 protein.
著者:: Chew, C, 等
出版事項: (2009)

Long alkylchain iminosugars block the HCV p7 ion channel
著者:: Pavlovic, D, 等
出版事項: (2005)

Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus.
著者:: Steinmann, E, 等
出版事項: (2007)

The Hepatitis C Virus E2p7 localization and topology in a recombinant system
著者:: Popescu, C, 等
出版事項: (2009)

Simulation approaches to ion channel gating
著者:: Biggin, P, 等
出版事項: (2002)

State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane
著者:: Dämgen, MA, 等
出版事項: (2021)

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment
著者:: Bharambe, Nikhil, 等
出版事項: (2024)

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment
著者:: Nikhil Bharambe, 等
出版事項: (2024-04-01)

Exploiting the defensive sugars of HIV-1 for drug and vaccine design
著者:: Scanlan, C, 等
出版事項: (2007)

Structure of the Human BK Ion Channel in Lipid Environment
著者:: Lige Tonggu, 等
出版事項: (2022-07-01)

State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane.
著者:: Marc A Dämgen, 等
出版事項: (2021-02-01)

Simulation approaches to ion channel structure-function relationships.
著者:: Tieleman, D, 等
出版事項: (2001)

Use of castanospermine and substituted-castonospermine compounds for treating hepatitis virus infections
著者:: Jacob, G, 等
出版事項: (2001)

Ion channel gating: insights via molecular simulations.
著者:: Beckstein, O, 等
出版事項: (2003)

Water in ion channels and pores--simulation studies.
著者:: Sansom, MS, 等
出版事項: (2002)

Clinical diagnosis of hepatic fibrosis using human serum APOL1 as biomarker
著者:: Gangadharan, B, 等
出版事項: (2012)

The p7 protein of hepatitis C virus forms structurally plastic, minimalist ion channels.
著者:: Danielle E Chandler, 等
出版事項: (2012-01-01)

Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope.
著者:: Cygan, N, 等
出版事項: (2011)

Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers
著者:: Gangadharan, B, 等
出版事項: (2008)

Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission.
著者:: Meredith, L, 等
出版事項: (2013)

Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
著者:: Gangadharan, B, 等
出版事項: (2010)

Voltage-Gated Lipid Ion Channels.
著者:: Andreas Blicher, 等
出版事項: (2013-01-01)

Novel serum biomarker candidates for liver fibrosis in hepatitis C patients
著者:: Gangadharan, B, 等
出版事項: (2007)

Potassium and sodium ions in a potassium channel studied by molecular dynamics simulations.
著者:: Biggin, P, 等
出版事項: (2001)

Sugar immunogens
著者:: Dwek, R, 等
出版事項: (2009)

Ion-channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7
著者:: Walter, S, 等
出版事項: (2016)

K(+) versus Na(+) ions in a K channel selectivity filter: a simulation study.
著者:: Shrivastava, I, 等
出版事項: (2002)

Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents
著者:: Zitzmann, N, 等
出版事項: (1999)

SIRT7 and hepatic lipid metabolism
著者:: Bor Luen eTang
出版事項: (2015-01-01)

The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.
著者:: Margaret A Scull, 等
出版事項: (2015-11-01)

Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling.
著者:: Simmons, A, 等
出版事項: (2005)

Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells.
著者:: Pollock, S, 等
出版事項: (2010)

Recent Insight into Lipid Binding and Lipid Modulation of Pentameric Ligand-Gated Ion Channels
著者:: Anna Ananchenko, 等
出版事項: (2022-06-01)

Inhibitor Development against p7 Channel in Hepatitis C Virus
著者:: Shukun Wei, 等
出版事項: (2021-03-01)

Modulation of a rapid neurotransmitter receptor-ion channel by membrane lipids
著者:: Francisco J. Barrantes
出版事項: (2024-01-01)