The ubiquitin-proteasome pathway is dysregulated in myeloma cells in the bone microenvironment in vivo

The ubiquitin-proteasome pathway is dysregulated in myeloma cells in the bone microenvironment in vivo

Manylion Llyfryddiaeth
Prif Awduron:	Edwards, C, Fowler, J, Caldwell, R, Bates, A, Edwards, JR, Zhang, J, Foehr, D, Parker, R, Roberts, A, Mundy, G
Fformat:	Conference item
Cyhoeddwyd:	2007

Eitemau Tebyg

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.
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Cyhoeddwyd: (2009)

Protein profiling in myeloma in vivo; Effects of bortezomib in a mouse model of myeloma
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Cyhoeddwyd: (2007)

The importance of the bone marrow microenvironment in multiple myeloma; Differential responses to lithium in vivo
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Cyhoeddwyd: (2006)

Decreased bone marrow-derived adiponectin contributes to myeloma pathogenesis in vivo
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Cyhoeddwyd: (2010)

Targeting Wnt signaling in myeloma in vivo; Differential effects on tumor burden and myeloma bone disease
gan: Edwards, C, et al.
Cyhoeddwyd: (2007)

Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo.
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Cyhoeddwyd: (2008)

Bone marrow stromal cells create a permissive microenvironment for myeloma development: a new stromal role for Wnt inhibitor Dkk1.
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Cyhoeddwyd: (2012)

Lithium inhibits the development of myeloma bone disease in vivo.
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Cyhoeddwyd: (2006)

Increasing adiponectin via an apolipoprotein peptide mimetic, L-4F, increases bone formation in normal mice and prevents myeloma bone disease in vivo
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A murine model of myeloma that allows genetic manipulation of the host microenvironment.
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Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases
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The Bone Marrow Microenvironment in Multiple Myeloma
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Myeloma cells decrease EphB4 expression in osteoblasts; A novel mechanism for regulation of bone formation in multiple myeloma
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Cyhoeddwyd: (2007)

Myeloma cells decrease EphB4 expression in osteoblasts: A novel mechanism for regulation of bone formation in multiple myeloma
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Cyhoeddwyd: (2007)

The antidiabetic drug metformin acts on the bone microenvironment to promote myeloma cell adhesion to preosteoblasts and increase myeloma tumour burden in vivo
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Cyhoeddwyd: (2021)

Host-derived MMP-7 decreases myeloma progression in vivo: An unexpected role for MMP-7 and osteopontin in myeloma pathogenesis
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Host Bone Marrow-Derived Stromal Cells Promote Myeloma Initiation and Development of Osteolysis
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Osteoclasts in Myeloma Are Derived from Gr-1(+)CD11b(+) Myeloid Immune Suppressor Cells of the Bone Marrow Niche in Vivo
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The pathogenesis of the bone disease of multiple myeloma.
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The antidiabetic drug metformin acts on the bone microenvironment to promote myeloma cell adhesion to preosteoblasts and increase myeloma tumour burden in vivo
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Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease.
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A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo
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Involvement of the ubiquitin-proteasome system in the regulation of the tumor microenvironment and progression
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Osteoclasts in myeloma are derived from Gr-1+CD11b+mononuclear cells of the bone marrow niche
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#38. Cholesterol increases bone marrow tumour burden in myeloma in vivo and promotes myeloma cell viability and bortezomib resistance ex vivo
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Tumor-host cell interactions in the bone disease of myeloma.
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Diet-induced obesity promotes a myeloma-like condition in vivo.
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EphB4 Expression in Osteoblasts is Regulated by Myeloma Cells and the Wnt Signaling Pathway.
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Agonists of TRAIL death receptors induce myeloma cell apoptosis that is not prevented by cells of the bone marrow microenvironment.
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The ubiquitin-proteasome system in the tumor immune microenvironment: a key force in combination therapy
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Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment
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Contribution of the Tumor Microenvironment to Metabolic Changes Triggering Resistance of Multiple Myeloma to Proteasome Inhibitors
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The KISS1 Receptor as an In Vivo Microenvironment Imaging Biomarker of Multiple Myeloma Bone Disease.
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Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
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Ubiquitin Proteasome System in Stress and Disease
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The Ubiquitin-Proteasome Pathway in Huntington's Disease
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Ubiquitin-proteasome system in diabetic retinopathy
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The Ubiquitin–Proteasome System in Immune Cells
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