The ubiquitin-proteasome pathway is dysregulated in myeloma cells in the bone microenvironment in vivo

Geahča maid

• Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.
  Dahkki: Edwards, C, et al.
  Almmustuhtton: (2009)
• Protein profiling in myeloma in vivo; Effects of bortezomib in a mouse model of myeloma
  Dahkki: Edwards, C, et al.
  Almmustuhtton: (2007)
• The importance of the bone marrow microenvironment in multiple myeloma; Differential responses to lithium in vivo
  Dahkki: Edwards, C, et al.
  Almmustuhtton: (2006)
• Decreased bone marrow-derived adiponectin contributes to myeloma pathogenesis in vivo
  Dahkki: Fowler, J, et al.
  Almmustuhtton: (2010)
• Targeting Wnt signaling in myeloma in vivo; Differential effects on tumor burden and myeloma bone disease
  Dahkki: Edwards, C, et al.
  Almmustuhtton: (2007)