PRC1 catalytic activity is central to Polycomb system function

The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects its target genes is poorly understood, and whether its histone-modifying activities are required for transcriptional repression remains cont...

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Hlavní autoři: Blackledge, NP, Fursova, NA, Kelley, JR, Huseyin, MK, Feldmann, A, Klose, RJ
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2019

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