PRC1 catalytic activity is central to Polycomb system function
The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects its target genes is poorly understood, and whether its histone-modifying activities are required for transcriptional repression remains cont...
Hlavní autoři: | Blackledge, NP, Fursova, NA, Kelley, JR, Huseyin, MK, Feldmann, A, Klose, RJ |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Elsevier
2019
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