A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study
<p><strong>Background:</strong> Differentiating between self-resolving viral infections and bacterial infections in children who are febrile is a common challenge, causing difficulties in identifying which individuals require antibiotics. Studying the host response to infe...
Main Authors: | Jackson, HR, Zandstra, J, Menikou, S, Hamilton, MS, McArdle, AJ, Fischer, R, Thorne, AM, Huang, H, Tanck, MW, Jansen, MH, De, T, Agyeman, PKA, Von Both, U, Carrol, ED, Emonts, M, Eleftheriou, I, Van der Flier, M, Fink, C, Gloerich, J, De Groot, R, Moll, HA, Pokorn, M, Pollard, AJ, Schlapbach, LJ, Tsolia, MN, Usuf, E, Wright, VJ, Yeung, S, Zavadska, D, Zenz, W, Coin, LJM, Casals-Pascual, C, Cunnington, AJ, Martinon-Torres, F, Herberg, JA, de Jonge, MI, Levin, M, Kuijpers, TW, Kaforou, M |
---|---|
其他作者: | PERFORM consortium |
格式: | Journal article |
语言: | English |
出版: |
Elsevier
2023
|
相似书籍
-
Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
由: Habgood-Coote, D, et al.
出版: (2023) -
Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe
由: Kolberg, L, et al.
出版: (2023) -
External validation of a multivariable prediction model for identification of pneumonia and other serious bacterial infections in febrile immunocompromised children
由: Martin, AJ, et al.
出版: (2023) -
Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study
由: Tan, CD, et al.
出版: (2023) -
Febrile illness in high-risk children: a prospective, international observational study
由: van der Velden, FJS, et al.
出版: (2022)