A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study

<p><strong>Background:</strong>&nbsp;Differentiating between self-resolving viral infections and bacterial infections in children who are febrile is a common challenge, causing difficulties in identifying which individuals require antibiotics. Studying the host response to infe...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Jackson, HR, Zandstra, J, Menikou, S, Hamilton, MS, McArdle, AJ, Fischer, R, Thorne, AM, Huang, H, Tanck, MW, Jansen, MH, De, T, Agyeman, PKA, Von Both, U, Carrol, ED, Emonts, M, Eleftheriou, I, Van der Flier, M, Fink, C, Gloerich, J, De Groot, R, Moll, HA, Pokorn, M, Pollard, AJ, Schlapbach, LJ, Tsolia, MN, Usuf, E, Wright, VJ, Yeung, S, Zavadska, D, Zenz, W, Coin, LJM, Casals-Pascual, C, Cunnington, AJ, Martinon-Torres, F, Herberg, JA, de Jonge, MI, Levin, M, Kuijpers, TW, Kaforou, M
Övriga upphovsmän: PERFORM consortium
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 2023