Expanding the use of primaquine for the radical cure of Plasmodium vivax

There is currently strong impetus for global malaria eradication with many National Malaria Control Programs setting ambitious elimination targets. Whilst intensified malaria control efforts have reduced the burden of falciparum malaria significantly, the fragile gains made thus far remain vulnerabl...

詳細記述

書誌詳細
主要な著者: Price, RN, Douglas, NM
フォーマット: Journal article
言語:English
出版事項: Oxford University Press 2018
その他の書誌記述
要約:There is currently strong impetus for global malaria eradication with many National Malaria Control Programs setting ambitious elimination targets. Whilst intensified malaria control efforts have reduced the burden of falciparum malaria significantly, the fragile gains made thus far remain vulnerable to the threat of emergence and spread of multidrug resistant parasites. Outside of Sub-Saharan Africa, the decline in falciparum malaria has also been shadowed by a rise in the proportion of malaria due to P. vivax, which is now the predominant cause of malaria in these regions. Vivax malaria is more difficult to eradicate than P. falciparum because it can form dormant liver stages (hypnozoites) that reactivate periodically, causing recurrent infections (relapses) and further transmission.