Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

Changes in monocyte subsets in volunteers who received an oral wild-type Salmonella Typhi challenge and reached typhoid diagnosis criteria

An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established allowing us to explore the development of immunity. In this model, ~55% of volunteers who received the challenge reached typhoid diagnosis criteria (TD), while ~45% did not (NoTD). Intestinal macrophages are o...

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Những tác giả chính:	Toapanta, FR, Hu, J, Shirey, KA, Bernal, PJ, Levine, MM, Darton, TC, Waddington, CS, Pollard, AJ, Sztein, MB
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Frontiers Media 2024

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